Combined Pharmacologic/Nonpharmacologic Intervention in Individuals at High Risk of Developing Type 2 Diabetes: Pro pharmacologic therapy
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چکیده
منابع مشابه
Combined Pharmacologic/Nonpharmacologic Intervention in Individuals at High Risk of Developing Type 2 Diabetes
The prevalence of type 2 diabetes continues to grow, and it is predicted that, unless effective prevention and control measures are implemented, the global prevalence of the disease will exceed 366 million by 2030 (1). Type 2 diabetes is associated with considerable morbidity, excess mortality, and substantial costs (2– 4). A recent statement issued by the American Diabetes Association estimate...
متن کاملRisk Assessment Tools for Identifying Individuals at Risk of Developing Type 2 Diabetes
Trials have demonstrated the preventability of type 2 diabetes through lifestyle modifications or drugs in people with impaired glucose tolerance. However, alternative ways of identifying people at risk of developing diabetes are required. Multivariate risk scores have been developed for this purpose. This article examines the evidence for performance of diabetes risk scores in adults by 1) sys...
متن کاملPharmacologic therapy for type 2 diabetes mellitus.
Type 2 diabetes mellitus is a chronic metabolic disorder that results from defects in both insulin secretion and insulin action. An elevated rate of basal hepatic glucose production in the presence of hyperinsulinemia is the primary cause of fasting hyperglycemia; after a meal, impaired suppression of hepatic glucose production by insulin and decreased insulin-mediated glucose uptake by muscle ...
متن کاملIncreased serum calcium levels and risk of type 2 diabetes in individuals at high cardiovascular risk.
OBJECTIVE Insulin resistance and secretion depend on calcium homeostasis. Cross-sectional studies have associated elevated serum calcium levels with markers of impaired glucose metabolism. However, only one prospective cohort study has demonstrated an increased risk of diabetes in individuals with increased serum calcium concentrations. The aim of the current study was to prospectively investig...
متن کاملA simple risk score identifies individuals at high risk of developing Type 2 diabetes: a prospective cohort study.
BACKGROUND Randomized trials have demonstrated that Type 2 diabetes is preventable among high-risk individuals. To date, such individuals have been identified through population screening using the oral glucose tolerance test. OBJECTIVE To assess whether a risk score comprising only routinely collected non-biochemical parameters was effective in identifying those at risk of developing Type 2 ...
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ژورنال
عنوان ژورنال: Diabetes Care
سال: 2009
ISSN: 0149-5992,1935-5548
DOI: 10.2337/dc09-s307